CHU Sherbrooke Research Centre Archives - Pediatric Research Foundation
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Biomarkers are indicators of change that measure transformations in a person’s metabolism. They are used to monitor and predict the health status of an individual or population so that an appropriate therapeutic intervention can be planned.Cytomegalovirus (CMV) is the most common cause of congenital infections worldwide. This infection has an estimated annual incidence of between […]

Principal investigator

  • Pr Christiane Auray-Blais, Professor, Faculty of Medicine and Health Sciences FMSS Department of Pediatrics, Université de Sherbrooke
  • Pr Michel Boutin, Department of pediatry, Sherbrooke

Perinatal, neonatal and obstetrics

Currently, the method for diagnosis and follow-up of pulmonary hypertension is echocardiography. Unfortunately, this examination requires significant technical skill, a cumbersome device, and patient manipulation. It is not uncommon for the newborn’s hypertension to worsen from the manipulations required to perform the examination. The purpose of this project is to evaluate the accuracy of pulmonary […]

Principal investigator

  • Dr Etienne Fortin, Professor, Faculty of Medicine and Health Sciences, FMSS Department of Pediatrics, Université de Sherbrooke

Metabolic and cardiovascular health

Sphingolipidoses include Gaucher’s disease, Krabbe’s disease, Fabry’s disease, Niemann-Pick (types A/B/C), metachromatic leukodystrophy, GM1 and GM2 gangliosidosis, Sandhoff disease and Farber disease.

Principal investigator

  • Pr Christiane Auray-Blais, Professor, Faculty of Medicine and Health Sciences FMSS Department of Pediatrics, Université de Sherbrooke

Metabolic and cardiovascular health

Congenital heart defects affect >1 in 100 children (60 times more common than cancer). They increase the risk of hospitalization by 20 times and are responsible for 4% of all hospital admissions in children.

Principal investigator

  • Dr Frederic Dallaire, Faculty of Medicine and Health Sciences FMSS Department of Pediatrics, Université de Sherbrooke

Metabolic and cardiovascular health

On a global scale, 5%–10% of pregnancies are complicated by hypertensive disorders of pregnancy (HDP), which can lead to serious maternal, fetal, and neonatal complications. Many of these women have pre-existing hypertension (<20 weeks of pregnancy) or hypertension postpartum that persists for more than 3 months. It has also been shown that women with a self-managed postpartum HDP are at high risk of developing chronic hypertension and cardiovascular complications later.

Principal investigator

  • Dr. Anne-Marie Côté

Perinatal, neonatal and obstetrics

Accountability

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While problematic eating attitudes and behaviours can surface during childhood and have extremely harmful effects over the long term, there have been no large-scale trials with enough participants to monitor children over a long period of time in order to identify and understand the psychosocial factors associated with the development of problematic eating attitudes and behaviours.

Principal investigator

  • Professor Isabelle Thibault, PhD in Clinical Sciences, Professor at the Faculty of Education and Psychoeducation, Université de Sherbrooke Research Centre

Metabolic and cardiovascular health Neurodevelopment and mental health

Accountability

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In a non-COVID context, 25% of children in primary school suffer from mental health issues. Recent reports illustrate, however, that the COVID-19 pandemic has led to a significant increase in the signs of anxiety and depression among youth.

Principal investigator

  • Professor Catherine Malboeuf-Hurtubise (Psychologist, Department of Psychology at Bishop’s University and CHUS Research Centre)

Neurodevelopment and mental health

Data from the Institut national de santé publique indicate that suicidal behaviours are increasing at an alarming rate in Quebec, especially among youth (Lévesque, Rassy and Genest, 2022). Girls aged 14 to 19 years make the most visits to the emergency room and are more often hospitalized for suicidal thoughts or suicide attempts. An increase […]

Principal investigator

  • Prof. Jessica Rassy, RN, PhD, Associate Professor and Researcher

Neurodevelopment and mental health