Funded Research Project Archive - Pediatric Research Foundation
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THE CONTEXT  Dravet syndrome is a severe genetic form of epilepsy affecting roughly one in every 15,700 births. It is caused by mutations in the SCN1A gene, which directs the production of an essential component of the channels that allow brain cells to transmit their electrical signals.  Children living with Dravet syndrome experience frequent, disabling […]

Principal investigator

  • Kenneth Myers

Rare and genetic diseases

Thank you to the Valsef Rêvons Grand Foundation (Valsef Dream Big Foundation), a Committed Donor, for supporting this research project. THE CONTEXT Screens now play an important role in the daily lives of teenagers in Quebec. Smartphones, social media, and digital platforms influence their relationships, activities, and access to information. Although excessive use is associated […]

Principal investigator

  • Dr. Richard Bélanger (Pediatrician, clinical researcher, Laval University)

Neurodevelopment and mental health

THE CONTEXT Perinatal mental health disorders, particularly depression and anxiety during pregnancy and after childbirth, are among the most common complications of the perinatal period. They affect up to one in five pregnant women and can have significant consequences for the mother’s health, the pregnancy, and the child’s development. When not identified and treated promptly, […]

Principal investigator

  • Prof Tina Montreuil, McGill University Research Center

Perinatal, neonatal and obstetrics

THE CONTEXT Polycystic ovary syndrome (PCOS) is the most common hormonal disorder affecting female fertility, affecting between 10 and 15 percent of women worldwide. In addition to compromising fertility and increasing the risk of complications during pregnancy, PCOS is associated with potential health consequences for children exposed to it in utero. Recent data suggest that […]

Principal investigator

  • Prof Mauro Silva, CHU de Québec

Child's health and human development

THE CONTEXT Over the past two decades, a marked increase in high levels of anxiety and depressive symptoms has been observed among adolescents and young adults, affecting up to 40% of this population according to large population surveys. The project will use data from more than 2,400 young adults in Quebec aged around 30, who […]

Principal investigator

  • Prof Geneviève Morneau-Vaillancourt, Banting Postdoctoral Fellow, Centre de recherche de l’Institut universitaire en santé mentale de Montréal (CR-IUSMM)

Neurodevelopment and mental health

THE CONTEXT Epilepsy is the most common chronic neurological condition in the world, affecting approximately 65 million people, including nearly 300,000 in Canada and 120,000 in Quebec. It usually manifests early in life: up to 85% of cases are diagnosed before adulthood. In children, epilepsy leads to chronic school absenteeism caused by seizures, medication side […]

Principal investigator

  • Dr. Alexander Weil, Department of Pediatric Neurosurgery, CHU Sainte-Justine
  • Prof. Sara Larivière, Department of Neuroscience, CHU de Sherbrooke

THE CONTEXT Developmental coordination disorder (DCD), also known as “dyspraxia,” is a neurodevelopmental condition that affects 5 to 6% of school-aged children and impacts motor performance and social participation. Young people with DCD have difficulty learning and performing motor skills and require more support and practice than their peers to carry out daily and physical […]

Principal investigator

  • Prof Emmanuelle Jasmin, CHU de Sherbrooke

Neurodevelopment and mental health

THE PROJECT Globalization and the digital revolution have brought about rapid changes in society, contributing to a rise in social inequalities and tensions between communities and identities. The COVID-19 pandemic has also amplified social polarization phenomena, increasing psychological distress, particularly among young people. Educational institutions (high schools, CEGEPs, universities) are not immune to this context […]

Principal investigator

  • Dr Cécile Rousseau, Full Professor in the Department of Psychiatry at McGill University and Director of the Department's Division of Child Psychiatry.

Neurodevelopment and mental health

THE PROJECT It is estimated that at least 15 to 20% of students are neurodivergent, meaning that their neurological profile is different from that of the majority, that their brain functions differently. The experience of these young people in schools is often described as difficult, complex and demanding. The self-esteem and mental health of many […]

Principal investigator

  • Pre Marie Grandisson, CHU de Québec

Neurodevelopment and mental health

PROJECT CONTEXT Premenstrual Dysphoric Disorder (PMDD) is a severe mood disorder that appears during the luteal phase of the menstrual cycle, affecting approximately 1.2 to 6.4% of women. It manifests as emotional instability, depressed mood, anxiety and irritability, leading to significant distress. This disorder affects between 20,000 and 90,000 young girls and women in Canada. […]

Principal investigator

  • Pr Hugo Théôret, Centre de recherche CHU Sainte -Justine
  • Pr Jean-François Lepage, Centre de recherche CHU de Sherbrooke

Neurodevelopment and mental health