Funded Research Project

Birth asphyxia and resulting neonatal encephalopathy (NE) in full-term babies is a major cause of death and severe neurodevelopmental disabilities, including cerebral palsy and intellectual disability.

This project involves an innovative approach using state-of-the-art techniques, including high-dimensional immunophenotyping combined with single-cell transcriptome analysis (CITE-seq), which allows for the simultaneous study of RNA and proteins from a single cell.

This project has several innovative elements. First, the concept of incidentally discovered asymptomatic VTE, or VTE, is largely unstudied in pediatrics, unlike its adult equivalent.

When a child is born very prematurely, the brain is not fully mature. Several crucial stages of brain development occur in the weeks following birth.

The World Health Organization has included global child health in its priorities for action to achieve marked and sustained improvements in the health of the world’s population by 2030.

Berger’s disease, also known as IgA nephropathy, is an autoimmune disease that damages a person’s kidneys. It affects between 2 and 10 out of every 100,000 people each year and although it often occurs in young adults, it may appear during childhood.

On a global scale, 5%–10% of pregnancies are complicated by hypertensive disorders of pregnancy (HDP), which can lead to serious maternal, fetal, and neonatal complications. Many of these women have pre-existing hypertension (<20 weeks of pregnancy) or hypertension postpartum that persists for more than 3 months. It has also been shown that women with a self-managed postpartum HDP are at high risk of developing chronic hypertension and cardiovascular complications later.

Accountability

-

While problematic eating attitudes and behaviours can surface during childhood and have extremely harmful effects over the long term, there have been no large-scale trials with enough participants to monitor children over a long period of time in order to identify and understand the psychosocial factors associated with the development of problematic eating attitudes and behaviours.

Accountability

-

A March 2020 review in The Lancet synthesizes previous literature examining the psychological impacts of lockdowns, including elevated levels of stress, anxiety, mood, and posttraumatic stress symptoms. Despite these findings in individuals, no studies to our knowledge have examined the psychological effects of lockdowns on children, families, and family functioning, the factors affecting positive and […]

Accountability

-

In a non-COVID context, 25% of children in primary school suffer from mental health issues. Recent reports illustrate, however, that the COVID-19 pandemic has led to a significant increase in the signs of anxiety and depression among youth.